As the demand for effective weight loss treatments continues to grow, Mounjaro has emerged as one of the most promising options available in the UK. Originally developed for type 2 diabetes management, it’s now gaining popularity as a highly effective medical weight loss solution.
In this article, we’ll break down everything you need to know about Mounjaro for weight loss – from how it works to what to expect during treatment.
Mounjaro (tirzepatide) is a once-weekly injectable medication that mimics the effects of two hormones: GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). These hormones help regulate blood sugar levels, control appetite, and improve insulin sensitivity.
Mounjaro is licensed in the UK for type 2 diabetes but is increasingly being used off-label for weight loss under the supervision of qualified healthcare professionals.
Mounjaro may be suitable for you if:
You are aged 18 or over
You have a BMI of 30 or higher, or 27+ with weight-related conditions (e.g., high blood pressure, PCOS)
You are committed to lifestyle changes, including diet and exercise
A consultation with a prescribing clinician is required to assess suitability and rule out any contraindications.
Mounjaro is administered as a once-weekly injection, typically in the abdomen or thigh. Patients usually start on a low dose (e.g. 2.5mg) and gradually increase to a higher maintenance dose over several weeks.
Your prescriber will create a personalised treatment plan based on your progress and response.
Month 1: Your body adjusts to the medication. Appetite begins to reduce.
Month 2–3: Noticeable weight loss and reduced portion sizes.
Month 4+: Weight loss continues steadily, especially with diet/exercise support.
Results vary, but consistency and follow-up are key to long-term success.
Common side effects include:
Nausea or upset stomach (often temporary)
Constipation or diarrhoea
Fatigue
Injection site irritation
Most symptoms improve as your body adjusts. Always report side effects to your prescriber.
Q: Is Mounjaro the same as Ozempic or Wegovy?
A: No – Mounjaro contains tirzepatide, whereas Ozempic and Wegovy contain semaglutide. Mounjaro targets two receptors (GLP-1 and GIP), making it potentially more effective.
Q: How much weight will I lose on Mounjaro?
A: Many patients lose between 10–20% of their body weight, but results depend on individual response, dosage, and lifestyle.
Mounjaro works in several ways to support weight loss:
Reduces appetite and food cravings
Slows gastric emptying, helping you feel fuller for longer
Improves blood sugar control, reducing insulin spikes
Encourages healthier eating habits over time
Clinical trials have shown weight loss of up to 20% of body weight in some patients, making it more effective than many other medications currently available.
